| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L004081
BDB004081
|
US20250388593, Example 229
CC(C)(C)OC(=O)CCCCCN1CC2(CC(=O)N(C3CCC(=O)NC3=O)C2=O)C1
|
C21H31N3O6 421.494000 |
DUCBXEHTNWZZPZ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM95475; PubChem:CID175638925
|
Local ready
Direct docking supported
|
|
E3L004082
BDB004082
|
US20250388593, Example 230
Nc1nccc(N2CC3(CC(=O)N(C4CCC(=O)NC4=O)C3=O)C2)n1
|
C15H16N6O4 344.331000 |
MXNVZOFEGIQCHN-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM95476; PubChem:CID175638926
|
Local ready
Direct docking supported
|
|
E3L004083
BDB004083
|
US20250388593, Example 231
CC(C)(C)OC(=O)c1ccc2nc(N3CC4(CC(=O)N(C5CCC(=O)NC5=O)C4=O)C3)sc2c1
|
C23H24N4O6S 484.534000 |
NAQASMAOVZPDFN-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM95477; PubChem:CID175638927
|
Local ready
Direct docking supported
|
|
E3L004084
BDB004084
|
US20250388593, Example 232
O=C1CCC(N2C(=O)CC3(CN(c4ccc([N+](=O)[O-])cc4)C3)C2=O)C(=O)N1
|
C17H16N4O6 372.337000 |
QQLKWJNBHKJMCZ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM95478; PubChem:CID177778567
|
Local ready
Direct docking supported
|
|
E3L004085
BDB004085
|
US20250388593, Example 233
CC(C)(C)OC(=O)NCCCNc1nccc(N2CC3(CC(=O)N(C4CCC(=O)NC4=O)C3=O)C2)n1
|
C23H31N7O6 501.544000 |
RUIOYQIVFYCFRJ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM95479; PubChem:CID178289697
|
Local ready
Direct docking supported
|
|
E3L004086
BDB004086
|
US20250388593, Example 234
CC(C)(C)OC(=O)COCCNc1nccc(N2CC3(CC(=O)N(C4CCC(=O)NC4=O)C3=O)C2)n1
|
C23H30N6O7 502.528000 |
KTDIYZDVHPRURD-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM95480; PubChem:CID178289698
|
Local ready
Direct docking supported
|
|
E3L004087
BDB004087
|
US20250388593, Example 235
Cn1ccc2c(N3CC4(CC(=O)N(C5CCC(=O)NC5=O)C4=O)C3)ncnc21
|
C18H18N6O4 382.380000 |
BUKOBNSXQCUWHI-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM95481; PubChem:CID175638930
|
Local ready
Direct docking supported
|
|
E3L004088
BDB004088
|
US20250388593, Example 236
CC(C)(C)OC(=O)NCCCCCCCCn1ccc2c(N3CC4(CC(=O)N(C5CCC(=O)NC5=O)C4=O)C3)ncnc21
|
C30H41N7O6 595.701000 |
TZWSCMSQKORQGQ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM95482; PubChem:CID177778575
|
Local ready
Direct docking supported
|
|
E3L004089
BDB004089
|
US20250388593, Example 237
CC(C)(C)OC(=O)N1CCC(Oc2ccc(CN3CC4(CC(=O)N(C5CCC(=O)NC5=O)C4=O)C3)cc2)CC1
|
C28H36N4O7 540.617000 |
ZZVUMBBQNNZODP-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM95483; PubChem:CID175638831
|
Local ready
Direct docking supported
|
|
E3L004090
BDB004090
|
US20250388593, Example 238
COc1ccc2nc(N3CC4(CC(=O)N(C5CCC(=O)NC5=O)C4=O)C3)sc2c1
|
C19H18N4O5S 414.443000 |
NPDBLLBHCKUWAF-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM95484; PubChem:CID175638832
|
Local ready
Direct docking supported
|
|
E3L004091
BDB004091
|
US20250388593, Example 239
COc1ccc2sc(N3CC4(CC(=O)N(C5CCC(=O)NC5=O)C4=O)C3)nc2c1
|
C19H18N4O5S 414.443000 |
QLHJILSADHLGTG-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM95485; PubChem:CID177778589
|
Local ready
Direct docking supported
|
|
E3L004092
BDB004092
|
US20250388593, Example 240
COc1cccc2sc(N3CC4(CC(=O)N(C5CCC(=O)NC5=O)C4=O)C3)nc12
|
C19H18N4O5S 414.443000 |
PGZWFIGQYBWMLV-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM95486; PubChem:CID175638834
|
Local ready
Direct docking supported
|
|
E3L004093
BDB004093
|
US20250388593, Example 241
CC(C)(C)OC(=O)NCCCCCOc1ccc2nc(N3CC4(CC(=O)N(C5CCC(=O)NC5=O)C4=O)C3)sc2c1
|
C28H35N5O7S 585.683000 |
HXMGLVGEFCVVQD-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM95487; PubChem:CID175638835
|
Local ready
Direct docking supported
|
|
E3L004094
BDB004094
|
US20250388593, Example 242
CC(C)(C)OC(=O)N1CCc2c(ncnc2N2CC3(CC(=O)N(C4CCC(=O)NC4=O)C3=O)C2)C1
|
C23H28N6O6 484.513000 |
SUYXZCICQNEHMU-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM95488; PubChem:CID177778482
|
Local ready
Direct docking supported
|
|
E3L004095
BDB004095
|
tert-Butyl 4-(3-fluoro-2,7-dioxoazepan-3-yl) benzoate
CC(C)(C)OC(=O)c1ccc(C2(F)CCCC(=O)NC2=O)cc1
|
C17H20FNO4 321.348000 |
WRHMYIYDNIUQNU-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM95489; PubChem:CID175638749
|
Local ready
Direct docking supported
|
|
E3L004096
BDB004096
|
N-[3-(3-Fluoro-2,7-dioxoazepan-3-yl) phenyl]acetamide
CC(=O)NC1=CC(C2(F)CCCC(=O)NC2=O)CC=C1
|
C14H17FN2O3 280.299000 |
OHLHUJXMCBWYTP-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM95490; PubChem:CID178289699
|
Local ready
Direct docking supported
|
|
E3L004097
BDB004097
|
3-(6-Oxo-3-phenylpyridazin-1-yl) azepane-2,7-dione
O=C1CCCC(n2nc(-c3ccccc3)ccc2=O)C(=O)N1
|
C16H15N3O3 297.314000 |
NGWNRNXNZRBQCW-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM95491; PubChem:CID171844156
|
Local ready
Direct docking supported
|
|
E3L004098
BDB004098
|
US20250388593, Example 247
O=C1CCCC(n2ncc(-c3ccccc3)cc2=O)C(=O)N1
|
C16H15N3O3 297.314000 |
MBAZGAYGMKQCDL-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM95492; PubChem:CID177778555
|
Local ready
Direct docking supported
|
|
E3L004099
BDB004099
|
US20250388593, Example 248
O=C1CCCC(n2ncc(Cl)cc2=O)C(=O)N1
|
C10H10ClN3O3 255.661000 |
OKJFJUWPAJZTFB-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM95493; PubChem:CID177778608
|
Local ready
Direct docking supported
|
|
E3L004100
BDB004100
|
US20250388593, Example 250
O=C1CCCC(n2nnc3ccccc32)C(=O)N1
|
C12H12N4O2 244.254000 |
QCKJOQJKNQHMOW-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM95494; PubChem:CID175638934
|
Local ready
Direct docking supported
|